[The Top 100 Drugs Clinical pharmacology and practical prescribing 2E] Listed by indication

Link: Second edition

Acne

  1. Tetracyclines

Acute coronary syndrome

  1. Angiotensin-converting enzyme (ACE) inhibitors
  2. Antiplatelet drugs, ADP-receptor antagonists
  3. Antiplatelet drugs, aspirin
  4. β-blockers
  5. Fibrinolytic drugs
  6. Heparins and fondaparinux
  7. Nitrates
  8. Opioids, strong
  9. Statins

Addison’s disease

  1. Corticosteroids (glucocorticoids), systemic

Adrenal insufficiency

  1. Corticosteroids (glucocorticoids), systemic

Agitation, psychomotor

  1. Antipsychotics, first-generation (typical)
  2. Antipsychotics, second-generation (atypical)

Alcohol withdrawal

  1. Benzodiazepines

Allergy

  1. Antihistamines (H1-receptor antagonists)
  2. Corticosteroids (glucocorticoids), systemic

Anaemia

  1. Iron
  2. Vitamins

Anaphylaxis

  1. Adrenaline (epinephrine)
  2. Antihistamines (H1-receptor antagonists)
  3. Corticosteroids (glucocorticoids), systemic

Angina

  1. β-blockers
  2. Calcium channel blockers
  3. Nitrates

Anxiety

  1. Antidepressants, selective serotonin reuptake inhibitors
  2. Antidepressants, venlafaxine and mirtazapine
  3. Benzodiazepines
  4. Gabapentin and pregabalin

Ascites

  1. Aldosterone antagonists
  2. Diuretics, loop
  3. Colloids (plasma substitutes)

Asthma

  1. Antimuscarinics, bronchodilators
  2. β2-agonists
  3. Corticosteroids (glucocorticoids), inhaled
  4. Leukotriene receptor antagonists

Atrial fibrillation and flutter

  1. Amiodarone
  2. β-blockers
  3. Calcium channel blockers
  4. Digoxin
  5. Direct oral anticoagulants
  6. Warfarin

Autoimmune disease

  1. Aminosalicylates
  2. Corticosteroids (glucocorticoids), systemic
  3. Methotrexate

Benign prostatic enlargement

  1. 5α-reductase inhibitors
  2. α-blockers

Bipolar disorder

  1. Antipsychotics, first-generation (typical)
  2. Antipsychotics, second-generation (atypical)
  3. Lamotrigine
  4. Valproate (valproic acid)

Bone metastases

  1. Bisphosphonates

Bowel preparation

  1. Laxatives, osmotic

Bradycardia

  1. Antimuscarinics, cardiovascular and gastrointestinal uses

Breast cancer

  1. Bisphosphonates
  2. Sex hormone antagonists for breast cancer

Breathlessness

  1. Diuretics, loop
  2. Opioids, strong

Carbon monoxide poisoning

  1. Oxygen

Cardiac arrest

  1. Adrenaline (epinephrine)
  2. Amiodarone
  3. Lidocaine

Chemotherapy

  1. Allopurinol
  2. Corticosteroids (glucocorticoids), systemic
  3. Methotrexate
  4. Antiemetics, serotonin 5-HT3-receptor antagonists

Chronic kidney disease

  1. Angiotensin receptor blockers
  2. Angiotensin-converting enzyme (ACE) inhibitors
  3. Calcium and vitamin D

Chronic obstructive pulmonary disease

  1. Antimuscarinics, bronchodilators
  2. β2-agonists
  3. Corticosteroids (glucocorticoids), inhaled

Circulatory compromise

  1. Colloids (plasma substitutes)
  2. Compound sodium lactate (Hartmann’s solution)
  3. Sodium chloride

Clostridium difficile colitis

  1. Metronidazole
  2. Vancomycin

Conjunctivitis, bacterial

  1. Aminoglycosides
  2. Chloramphenicol

Constipation

  1. Laxatives, osmotic
  2. Laxatives, stimulant

Contrast nephropathy

  1. Acetylcysteine (N-acetylcysteine)

Contraception, hormonal

  1. Oestrogens and progestogens

Deep vein thrombosis

  1. Direct oral anticoagulants
  2. Heparins and fondaparinux
  3. Warfarin

Dementia

  1. Acetylcholinesterase inhibitors

Dental infection

  1. Metronidazole

Depression

  1. Antidepressants, selective serotonin reuptake inhibitors
  2. Antidepressants, tricyclics and related drugs
  3. Antidepressants, venlafaxine and mirtazapine

Diabetes mellitus

  1. Dipeptidylpeptidase-4 inhibitors
  2. Insulin
  3. Metformin
  4. Sulphonylureas

Diabetic ketoacidosis

  1. Insulin

Diabetic nephropathy

  1. Angiotensin receptor blockers
  2. Angiotensin-converting enzyme (ACE) inhibitors

Diarrhoea

  1. Antimotility drugs 70

Dry eyes

  1. Ocular lubricants (artificial tears)

Dry skin

  1. Emollients

Dyspepsia

  1. Alginates and antacids
  2. H2-receptor antagonists
  3. Proton pump inhibitors

Eczema

  1. Corticosteroids (glucocorticoids), topical
  2. Emollients

Endocarditis

  1. Aminoglycosides
  2. Penicillins
  3. Penicillins, penicillinase-resistant
  4. Vancomycin

Epilepsy, absence seizures

  1. Valproate (valproic acid)

Epilepsy, focal

  1. Carbamazepine
  2. Gabapentin and pregabalin
  3. Lamotrigine
  4. Levetiracetam
  5. Valproate (valproic acid)

Epilepsy, generalised

  1. Carbamazepine
  2. Lamotrigine
  3. Valproate (valproic acid)

Epilepsy, status epilepticus

  1. Benzodiazepines
  2. Levetiracetam
  3. Valproate (valproic acid)

Erectile dysfunction

  1. Phosphodiesterase (type 5) inhibitors

Faecal impaction

  1. Laxatives, osmotic
  2. Laxatives, stimulant

Fever

  1. Antiplatelet drugs, aspirin
  2. Paracetamol

Fluid and electrolyte therapy

  1. Colloids (plasma substitutes)
  2. Compound sodium lactate (Hartmann’s solution)
  3. Glucose (dextrose)
  4. Potassium chloride
  5. Sodium chloride

Gastro-oesophageal reflux disease

  1. Alginates and antacids
  2. H2-receptor antagonists
  3. Proton pump inhibitors

Generalised anxiety disorder

  1. Antidepressants, venlafaxine and mirtazapine
  2. Gabapentin and pregabalin

Glaucoma, open-angle

  1. Prostaglandin analogue eye drops

Gout

  1. Allopurinol
  2. Non-steroidal antiinflammatory drugs

Hay fever (seasonal allergic rhinitis)

  1. Antihistamines (H1-receptor antagonists)

Heart failure

  1. Aldosterone antagonists
  2. Angiotensin receptor blockers
  3. Angiotensin-converting enzyme (ACE) inhibitors
  4. β-blockers
  5. Digoxin
  6. Diuretics, loop

Heart valve replacement

  1. Warfarin

Helicobacter pylori eradication

  1. Macrolides
  2. Penicillins, broad-spectrum
  3. Proton pump inhibitors

Hepatic encephalopathy

  1. Laxatives, osmotic

Herpesvirus infection

  1. Antiviral drugs

Hormonal contraception

  1. Oestrogens and progestogens

Hormone replacement therapy

  1. Oestrogens and progestogens

Hyperaldosteronism

  1. Aldosterone antagonists

Hypercalcaemia of malignancy

  1. Bisphosphonates

Hyperglycaemic hyperosmolar syndrome

  1. Insulin

Hyperkalaemia

  1. β2-agonists
  2. Calcium and vitamin D
  3. Glucose (dextrose)
  4. Insulin

Hyperlipidaemia

  1. Statins

Hypertension

  1. α-blockers
  2. Angiotensin receptor blockers
  3. Angiotensin-converting enzyme (ACE) inhibitors
  4. β-blockers
  5. Calcium channel blockers
  6. Diuretics, thiazide and thiazide-like

Hyperuricaemia

  1. Allopurinol

Hypocalcaemia

  1. Calcium and vitamin D

Hypoglycaemia

  1. Glucose (dextrose)

Hypokalaemia

  1. Potassium chloride

Hypopituitarism

  1. Corticosteroids (glucocorticoids), systemic
  2. Thyroid hormones

Hypothyroidism

  1. Thyroid hormones

Hypoxaemia

  1. Oxygen

Incontinence, urinary

  1. Antimuscarinics, genitourinary uses

Infection, complicated

  1. Cephalosporins and carbapenems
  2. Penicillins, antipseudomonal

Infection, fungal

  1. Antifungal drugs

Infection, protozoal

  1. Metronidazole

Infection, viral

  1. Antiviral drugs

Inflammation

  1. Corticosteroids (glucocorticoids), systemic
  2. Corticosteroids (glucocorticoids), inhaled
  3. Corticosteroids (glucocorticoids), topical
  4. Non-steroidal antiinflammatory drugs

Inflammatory bowel disease

  1. Aminosalicylates
  2. Azathioprine
  3. Corticosteroids (glucocorticoids), systemic

Insomnia

  1. Benzodiazepines
  2. Z-drugs

Irritable bowel syndrome

  1. Antimuscarinics, cardiovascular and gastrointestinal uses

Ischaemic heart disease

  1. Angiotensin receptor blockers
  2. Angiotensin-converting enzyme (ACE) inhibitors
  3. Antiplatelet drugs, ADP-receptor antagonists
  4. Antiplatelet drugs, aspirin
  5. β-blockers
  6. Fibrinolytic drugs
  7. Statins

Keratoconjunctivitis sicca

  1. Ocular lubricants (artificial tears)

Korsakoff’s psychosis

  1. Vitamins

Leg cramps

  1. Quinine

Local anaesthesia

  1. Adrenaline (epinephrine)
  2. Lidocaine

Lyme disease

  1. Tetracyclines

Malaria

  1. Quinine

Meningitis

  1. Cephalosporins and carbapenems
  2. Penicillins

Migraine

  1. Serotonin 5-HT1-receptor agonists

Mucosal bleeding

  1. Adrenaline (epinephrine)

Myeloma

  1. Bisphosphonates

Nausea and vomiting

  1. Antiemetics, dopamine D2-receptor antagonists
  2. Antiemetics, histamine H1-receptor antagonists
  3. Antiemetics, serotonin 5-HT3-receptor antagonists
  4. Antipsychotics, first-generation (typical)

Neural tube defects, prevention of

  1. Vitamins

Obsessive compulsive disorder

  1. Antidepressants, selective serotonin reuptake inhibitors

Ocular hypertension

  1. Prostaglandin analogue eye drops

Oedema

  1. Diuretics, loop

Opioid toxicity

  1. Naloxone

Osteomyelitis

  1. Penicillins, penicillinase-resistant
  2. Vancomycin

Osteoporosis

  1. Bisphosphonates
  2. Calcium and vitamin D

Otitis externa

  1. Aminoglycosides
  2. Chloramphenicol

Otitis media

  1. Penicillins, broad-spectrum

Overdose

  1. Acetylcysteine (N-acetylcysteine)
  2. Activated charcoal

Paget’s disease

  1. Bisphosphonates

Pain

  1. Non-steroidal antiinflammatory drugs
  2. Opioids, strong
  3. Opioids, weak/moderate
  4. Paracetamol

Pain, neuropathic

  1. Antidepressants, tricyclics and related drugs
  2. Gabapentin and pregabalin

Panic disorders

  1. Antidepressants, selective serotonin reuptake inhibitors

Paracentesis

  1. Colloids (plasma substitutes)

Parkinsonism, secondary

  1. Dopaminergic drugs for Parkinson’s disease

Parkinson’s disease

  1. Dopaminergic drugs for Parkinson’s disease

Parkinson’s disease, associated dementia

  1. Acetylcholinesterase inhibitors

Peptic ulcer disease

  1. H2-receptor antagonists
  2. Proton pump inhibitors

Peripheral arterial disease

  1. Antiplatelet drugs, ADP-receptor antagonists
  2. Antiplatelet drugs, aspirin

Pneumonia

  1. Cephalosporins and carbapenems
  2. Macrolides
  3. Metronidazole
  4. Penicillins
  5. Penicillins, antipseudomonal
  6. Penicillins, broad-spectrum
  7. Quinolones
  8. Tetracyclines

Pneumonia, pneumocystis

  1. Trimethoprim (with sulfamethoxazole)

Pneumothorax

  1. Oxygen

Poisoning

  1. Acetylcysteine (N-acetylcysteine)
  2. Activated charcoal
  3. Benzodiazepines
  4. Naloxone
  5. Oxygen
  6. Vitamins

Pruritus

  1. Antihistamines (H1-receptor antagonists)

Psoriasis

  1. Emollients
  2. Methotrexate

Psychomotor agitation

  1. Antipsychotics, first-generation (typical)
  2. Antipsychotics, second-generation (atypical)

Pulmonary embolus

  1. Direct oral anticoagulants
  2. Fibrinolytic drugs
  3. Heparins and fondaparinux
  4. Warfarin

Pulmonary hypertension

  1. Phosphodiesterase (type 5) inhibitors

Pulmonary oedema

  1. Diuretics, loop
  2. Nitrates
  3. Opioids, strong

Pyelonephritis

  1. Aminoglycosides
  2. Penicillins, broad-spectrum

Reconstitution and dilution of drugs

  1. Glucose (dextrose)
  2. Sodium chloride

Respiratory secretions

  1. Acetylcysteine (N-acetylcysteine)
  2. Antimuscarinics, cardiovascular and gastrointestinal uses

Rheumatoid arthritis

  1. Aminosalicylates
  2. Azathioprine
  3. Methotrexate
  4. Non-steroidal antiinflammatory drugs

Schizophrenia

  1. Antipsychotics, first-generation (typical)
  2. Antipsychotics, second-generation (atypical)

Sedation

  1. Benzodiazepines

Sepsis

  1. Aminoglycosides
  2. Cephalosporins and carbapenems
  3. Penicillins
  4. Penicillins, antipseudomonal
  5. Vancomycin

Sepsis, intraabdominal

  1. Aminoglycosides
  2. Metronidazole
  3. Penicillins, antipseudomonal
  4. Penicillins, broad-spectrum

Septic arthritis

  1. Penicillins, penicillinase-resistant

Shock

  1. Colloids (plasma substitutes)
  2. Compound sodium lactate (Hartmann’s solution)
  3. Sodium chloride

Skin and soft tissue infection

  1. Macrolides
  2. Penicillins
  3. Penicillins, antipseudomonal
  4. Penicillins, penicillinase-resistant

Sjögren’s syndrome

  1. Ocular lubricants (artificial tears)

Smoking cessation

  1. Nicotine replacement and related drugs

Stroke

  1. Antiplatelet drugs, ADP-receptor antagonists
  2. Antiplatelet drugs, aspirin
  3. Fibrinolytic drugs

Subacute combined degeneration of the cord

  1. Vitamins

Supraventricular tachycardia

  1. Adenosine
  2. Amiodarone
  3. β-blockers
  4. Calcium channel blockers

Tetanus

  1. Penicillins

Thiamine deficiency

  1. Vitamins

Tonsillitis

  1. Penicillins

Trigeminal neuralgia

  1. Carbamazepine

Tumour lysis syndrome

  1. Allopurinol

Ulcerative colitis

  1. Aminosalicylates

Urinary catheterisation

  1. Lidocaine

Urinary tract infection

  1. Cephalosporins and carbapenems
  2. Nitrofurantoin
  3. Penicillins, antipseudomonal
  4. Penicillins, broad-spectrum
  5. Quinolones
  6. Trimethoprim

Urticaria

  1. Antihistamines (H1-receptor antagonists)

Venous thromboembolism, prophylaxis

  1. Direct oral anticoagulants
  2. Heparins and fondaparinux

Venous thromboembolism, treatment

  1. Direct oral anticoagulants
  2. Fibrinolytic drugs
  3. Heparins and fondaparinux
  4. Warfarin

Ventricular fibrillation

  1. Adrenaline (epinephrine)
  2. Amiodarone
  3. Lidocaine

Ventricular tachycardia

  1. Adrenaline (epinephrine)
  2. Amiodarone
  3. Lidocaine

Vitamin D deficiency

  1. Calcium and vitamin D

Vitamin K deficiency bleeding

  1. Vitamins

Warfarin, reversal of

  1. Vitamins

Wernicke’s encephalopathy

  1. Vitamins

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