Wednesday, 23 January 2019

Osler's node

Osler's nodes are medical signs.

Features

  • Tender
  • Erythematous 
  • Raised
  • Lesions on the palms or soles 

 

Pathophysiology

  • Antibody binds to antigen  
  • Immune complexes form 
  • Complexes are deposited in the tissues  
  • Immune complexes trigger tissue inflammation 

 

Causes

  • Infective endocarditis
  • Systemic lupus erythematosus
  • Marantic endocarditis
  • Disseminated gonococcal infection
  • Distal to infected arterial catheter

 

See also

  • Osler's node

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