Phaeochromocytoma

A phaeochromocytoma is a neoplasm of the adrenal medulla.

 

Pathophysiology

This produces excessive catecholamines, mostly norepinephrine and a significant amount of epinephrine.
The adrenergic signalling results in sympathetic nervous system hyperactivity. 

 

Symptoms and signs

• Secondary refractory hypertension
• Sinus tachycardia 
• Heart palpitations
• Chest pain 
• Anxiety
• Sweating