Saturday, 12 December 2020

History of medicine: 21st century

2000s decade

  • February 2004 : First licensing of an angiogenesis inhibitor therapy for cancer: bevacizumab.
  • November 2008 : First live birth resulting from whole ovarian transplantation. 

2010s decade

  • March 2010: First full-face transplantation.
  • January 2011 : Case report of successful skin regeneration after using a 'skin gun'  spray cells onto deep dermal burns.
  • March 2011 : First clinical trial (Phase 1) of human genetic engineering: blood was extracted from the patients, the T-cells were altered (by zinc-finger nucleases) and then transfused back into the body.
  • July 2013 : Vascularized and functional human liver tissue was generated from human induced pluripotent stem cells by transplantation of liver buds created in vitro.
  • October 2014 : First uterine transplantation to result in a live birth.
  • December 2014 : First successful transplantation of neonatal organs.
  • November 2017 : First publication of a regeneration of the entire human epidermis using transgenic stem cells.
  • 2018 : Patients regained voluntary control of paralysed muscles after a course of temporospatially selective spinal cord stimulation and physical therapy.
  • September 2018 : First report of in-body human genetic engineering (zinc-finger nucleases). 
  • October 2018 : Researchers teach a deep convolutional neural network to distinguish between two types of lung cancer and normal lung tissue from histopathology slides.
  • November 2018 : First report of gene edited embryos implanted inside a pregnant woman.
  • July 2019 : Publication of a prospective case series of nerve transfer surgery. It reported successful grafting of nerves to correct upper limb function in tetraplegic patients. 
  • 24-27 December 2019: First identification of SARS-CoV2, the causative organism in the COVID19 pandemic.

2020s decade

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