Neoplasms by Histologic Type

Disease class: Neoplasms 

Types

• histiocytic disorders, Malignant
• Leukaemia
• Lymphatic vessel tumors 
• Lymphoma
• neoplasms, Complex and Mixed
• neoplasms, Connective and Soft tissue
• neoplasms, Germ cell and Embryonal
• neoplasms, Glandular and Epithelial
• neoplasms, Gonadal tissue
• neoplasms, Nerve tissue 
• neoplasms, Plasma cell
• neoplasms, Vascular tissue
• Naevi and Melanomas
• Odontogenic tumors  

 

What is a histological type?

• Neoplasm = new growth. Every neoplasm arises from an original human cell.
• Some neoplasms can be categorised by anatomical site (e.g. lung cancer), but some cannot (e.g. white blood cells).
• Histology is the microscopic and molecular analysis of a sample of tissue or cells.
• Through histology, most cancers can be classified as a "histological type" (e.g. a B-cell lymphoma).

 

For example

• First known site of lymphadenopathy: cervical lymph node 
• Present in: lymph fluid, lymphatic vessels, multiple lymph nodes
• Not detected in: blood, organs
• Anatomical site of origin: ???
• Histological analysis: 
• Lymph node biopsy sample
• Lymphocytic morphology
• Lymphoma
• No Reed-sternberg cells seen
• Non-Hodgkin lymphoma
• CD-19 positive
• B-cell
• CD-20 positive
• B-cell
• Other features
• Diagnosis: lymphoma, large B-cell, Diffuse