Also known as CKD.
Ageing decline
As people age, their renal function (the work done by the kidneys) declines because the number of nephrons (the functional subunit of the kidney) declines. This doesn't significantly affect most people, but for some people the kidney function reaches a threshold where they are diagnosed with CKD: chronic kidney disease.
Chronic kidney disease
Once
CKD reaches a high stage, patients experience a myriad of problems
related to the liver: anaemia (a deficiency of red blood cells),
osteoporosis (bone weakness and easy fracturing), oedema (fluid
retention) and
anasarca (widespread fluid retention throughout the whole body).
Impact on care
Exogenous
drugs (medications) are only safe if the body can remove them at a
sufficient rate, and a patient with even early stage CKD might no longer
be suitable to take certain medications.
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