MeSH disease class: Hypertension
MeSH disease class: Retinal diseases
A common degenerative condition, caused by chronic uncontrolled hypertension.
Causes
Pathophysiology
- The pressure of the fluid in the circulatory system is too high.
- The forces transmitted by the circulating bloodstream to the vessels are high enough to cause vascular damage.
- Arterioles in the eyes become damaged and atherosclerosis develops. They thicken and shorten.
- Vessels rupture and haemorrhage into the eye.
- Areas of the retina become ischaemic and appear pale.
Signs on fundoscopy
Arteriolar changes
- Copper wire arterioles : The arterioles appear a bright metallic orange, like copper. The central light reflex is seen across part of the width of the arteriole.
- Silver wire arterioles : The arterioles appear a bright metallic white, like silver. The central light reflex is seen across the entire width of the arteriole.
- Arteriovenous (AV) nicking : The venules are by compressed by arterioles, as if they are being nicked or nipped. This appears as a point of tight constriction of a vein, with bulging of the vein on both sides of the constriction.
- Salus sign: At points of intersection with arterioles, the course of the venule is deflected and appears irregular. The venule is bent around the arteriole like a horseshoe bent around a stake. The course of the venule is deflected and appears irregular. This happens due to tension on the venule as the arteriole shortens.
Advanced retinopathy lesions
- Microaneurysms
- Blot hemorrhages
- Flame hemorrhages
- Ischaemic changes (e.g. cotton wool spots)
- Hard exudates
- Optic disc oedema: Swelling of the optic disc
- Macular star: a ring of exudates around the retina
Grading
- Keith Wagener Barker (KWB) Grades 1-4
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