Sunday, 27 January 2019

Hypertensive retinopathy

MeSH disease class: Hypertension
 MeSH disease class: Retinal diseases

A common degenerative condition, caused by chronic uncontrolled hypertension.

Causes

Pathophysiology

  • The pressure of the fluid in the circulatory system is too high.
  • The forces transmitted by the circulating bloodstream to the vessels are high enough to cause vascular damage.
  • Arterioles in the eyes become damaged and atherosclerosis develops. They thicken and shorten.
  • Vessels rupture and haemorrhage into the eye.
  • Areas of the retina become ischaemic and appear pale.

 

Signs on fundoscopy

Arteriolar changes

  • Copper wire arterioles : The arterioles appear a bright metallic orange, like copper. The central light reflex is seen across part of the width of the arteriole.
  • Silver wire arterioles : The arterioles appear a bright metallic white, like silver. The central light reflex is seen across the entire width of the arteriole.
  • Arteriovenous (AV) nicking : The venules are by compressed by arterioles, as if they are being nicked or nipped. This appears as a point of tight constriction of a vein, with bulging of the vein on both sides of the constriction.
  • Salus sign: At points of intersection with arterioles, the course of the venule is deflected and appears irregular. The venule is bent around the arteriole like a horseshoe bent around a stake. The course of the venule is deflected and appears irregular. This happens due to tension on the venule as the arteriole shortens.

Advanced retinopathy lesions

  • Microaneurysms
  • Blot hemorrhages 
  • Flame hemorrhages
  • Ischaemic changes (e.g. cotton wool spots)
  • Hard exudates
  • Optic disc oedema: Swelling of the optic disc
  • Macular star: a ring of exudates around the retina

 

Grading

  • Keith Wagener Barker (KWB) Grades 1-4

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