Kawasaki disease

Systemic vasculitis

Also known as

Mucocutaneous lymph node syndrome

Pathophysiology 

Kawasaki disease (KD) often causes irritation and ulceration at mucosal surfaces.

These patients often present with skin rashes, lymphadenopathy, tongue swelling, desquamation of the palms and soles, lip swelling, conjunctival injection (prominent vessels in the sclera of the eyes), gastrointestinal symptoms.

In 20-40% of patients, the coronary arteries are affecting, potentially causing chest pain and breathlessness.

This disease usually occurs in young children (<5 years old).