Monoclonal Gammopathy of Undetermined Significance

Disease class: Hypergammaglobulinaemia
Disease class: Paraproteinaemias

Also known as

• MGUS

This refers to a plasma cell dyscrasia, in which abnormal excessive levels of gamma globulins are detected in the blood. There are no symptoms, but the patient has an increased risk of progression to malignancies such as multiple myeloma. One study found that the risk of progression to malignancy was 11% (6.5 times higher than the general population).

 

Monoclonal gammopathies

• Monoclonal Gammopathy of Undetermined Significance  
• Smouldering multiple myeloma
• Multiple myeloma