Multiple Myeloma is a malignancy of plasma cells.
Epidemiology
- This is the 19th most common cancer in the UK.
Investigations
- X-ray imaging of the skull: "Raindrop skull" appearance, due to lytic bone lesions.
- Urine electrophoresis: positive for Bence Jones protein. This was originally done by heating a urine specimen to cause protein precipitation. More recently, they are detected by electrophoresis of concentrated urine or serum free light chain assays.
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