Severe acute respiratory syndrome coronavirus

Pathogen category: (+)ssRNA viruses

Also known as

• SARS-CoV-1
• SARS virus
  

 

Pathology

• Severe Acute Respiratory Syndrome (SARS)
  

 

Features

Exploits

• ACE2 (Angiotensin Converting Enzyme 2). An cell surface enzyme. The viral spike protein has evolved a Receptor Binding Domain, with high binding affinity for ACE2.
  
• TMPRSS2 (Transmembrane protease, serine 2): A transmembrane enzyme. SARS-CoV1 and SARS-CoV2 have evolved to initiate cell entry when they interact with this enzyme on the cell surface.

 

Taxonomy

• Category: Virus     
• Realm: Riboviria
• Kingdom: Orthornavirae
• Phylum: Pisuviricota
• Class: Pisoniviricetes
• Order: Nidovirales
• Family: Coronaviridae
• Genus: Betacoronavirus
• Subgenus: Sarbecovirus
• Species: Severe acute respiratory syndrome–related coronavirus

 

See also

• Severe acute respiratory syndrome coronavirus 2 (a later strain.)