Paraneoplastic syndromes
Types
- ACTH syndrome, Ectopic
- Zollinger–Ellison syndrome
Pathophysiology
- Small cell lung cancer : production of anti-diuretic hormone (ADH) : syndrome of inappropriate antidiuretic hormone secretion (SIADH)
- Pituitary adenoma : production of human growth hormone (hGH) : acromegaly or pituitary gigantism
- Parathyroid adenoma : production of parathyroid hormone (PTH) : primary hyperparathyroidism
- Phaeochromocytoma : production of catecholamines : sympathetic nervous system hyperactivity.
- Gastrinoma : production of gastrin : pancreatic ulcerogenic tumor syndrome (Zollinger–Ellison syndrome).
- Carcinoid tumour : production of several signalling molecules, predominantly serotonin and kallikrein : Carcinoid syndrome
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