Tuesday, 12 February 2019

Anti-NMDA receptor antibodies

This is a test for an antibody (immunoglobulin) in the serum.

N-methyl-D-aspartate (NMDA) receptor antibodies are associated with the different sub units of the NMDA receptor.

 

Clinical indications:

  • Antibodies to the delta or NR2 subunits of NMDAR are associated with limbic encephalitis, systemic lupus erythematosus (SLE), ataxia and epilepsia partialis continua. 
  • Antibodies against the NR1, NR2A and NR2B subunits of the NMDAR are found in patients presenting with psychiatric symptoms, amnesia, seizures, dyskinesias, autonomic dysfunction and loss of consciousness. 
  • Antibodies against the NR1 or NR2 subunits of the NMDAR: Anti-NMDA receptor encephalitis

 

Specimen type: 

Blood

Sample type: 

Serum (can be paired with CSF sample)

Turnaround time: 

3 weeks

 

Immunology homepage 

No comments:

Post a Comment