N-methyl-D-aspartate (NMDA) receptor antibodies are associated with the different sub units of the NMDA receptor.
Clinical indications:
- Antibodies to the delta or NR2 subunits of NMDAR are associated with limbic encephalitis, systemic lupus erythematosus (SLE), ataxia and epilepsia partialis continua.
- Antibodies against the NR1, NR2A and NR2B subunits of the NMDAR are found in patients presenting with psychiatric symptoms, amnesia, seizures, dyskinesias, autonomic dysfunction and loss of consciousness.
- Antibodies against the NR1 or NR2 subunits of the NMDAR: Anti-NMDA receptor encephalitis
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