Monday, 22 April 2019

Dupuytren contracture

Disease class: Connective tissue diseases
Disease class: Contracture

Also known as
Viking's disease

Signs and symptoms
Lateral digits (little finger and ring finger) are stuck in flexion. 

Pathophysiology
The movements of the affected tendons are restricted by thickening of the fibrous tissue. 

Risk factors
Associated with alcoholic liver disease. 

Genomics
More common in population descended from Viking settlers due to the founder effect. 

Management
Surgical release of tendons

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