Stiff-Person syndrome

Disease class:  Autoimmune diseases of the nervous system
Disease class: Neuromuscular diseases 

Disease class: Spinal cord diseases

Also known as SPS.

A rare neurological disease characterised by muscle rigidity and spasms. 

 

Pathophysiology

Anti-GAD antibodies are associated with both SPS and type I diabetes.
About 35 percent of SPS patients also have T1D.

 

Investigations

• Anti-GAD