Hypercalcaemia

Disease class: Calcium metabolism disorders
Disease class: Water-electrolyte imbalance

Definition

• This refers to calcium levels in the blood above the reference range.

 

Causes

• Hyperparathyroidism
• Neoplasms
• Lymphoma
• Sarcoidosis
• Tuberculosis
• Vitamin D poisoning
• Multiple myeloma 
• Vitamin A poisoning
• Hyperthyroidism

 

Management

Diagram created by uptodate.com

Investigations

1. Serum calcium
2. Total corrected calcium
3. Intact parathyroid hormone (PTH)
4. PTHrP
5. Chest radiograph
6. CT-thorax scan
7. 1,25-dihydroxyvitamin D
8. Lymph node biopsy
9. 25-hydroxyvitamin D
10. SPEP
11. UPEP
12. Serum free light chain assay

 

See also

• Hypocalcaemia